2460957-52-0

2460957-52-0 structure

2460957-52-0 structure

Name: HBV-IN-21
Chemical Name: HBV-IN-21
CAS Number: 2460957-52-0
Molecular Formula: C₁₇H₁₇FN₄OS₂
Molecular Weight: 376.47
Catalog: Signaling Pathways Anti-infection HBV
Create Date: 2022-07-11 08:56:51
Modify Date: 2024-01-13 20:04:41
HBV-IN-21 (Compound II-8b) is an HBV DNA replication inhibitor with an IC50 of 2.2 µM. HBV-IN-21 can interact HBV 4 capsid protein with good affinity (KD = 60.0 μM)[1].

Name	HBV-IN-21

Description	HBV-IN-21 (Compound II-8b) is an HBV DNA replication inhibitor with an IC50 of 2.2 µM. HBV-IN-21 can interact HBV 4 capsid protein with good affinity (KD = 60.0 μM)[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> HBV Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis
Target	IC50: 2.2 µM (HBV DNA replication)[1]
References	[1]. Jia H, et al. Design, diversity-oriented synthesis and biological evaluation of novel heterocycle derivatives as non-nucleoside HBV capsid protein inhibitors. Eur J Med Chem. 2020 Sep 15;202:112495.

Molecular Formula	C₁₇H₁₇FN₄OS₂
Molecular Weight	376.47