2445349-54-0

2445349-54-0 structure

Name: Keap1-Nrf2-IN-10
Chemical Name: Keap1-Nrf2-IN-10
CAS Number: 2445349-54-0
Molecular Formula: C₂₅H₂₂I₂N₄O₇S₂
Molecular Weight: 808.40
Catalog: Research Areas Others
Create Date: 2022-07-02 18:56:26
Modify Date: 2024-09-17 10:11:54
Keap1-Nrf2-IN-10 (compound 15) is a potent NQO1 inducer. Keap1-Nrf2-IN-10 inhibits oxidative stress by decreasing the levels of MDA, ROS, NQO1 in the liver for gamma-irradiated mice. Keap1-Nrf2-IN-10 improves the survival of gamma-irradiated mice[1].

Name	Keap1-Nrf2-IN-10

Description	Keap1-Nrf2-IN-10 (compound 15) is a potent NQO1 inducer. Keap1-Nrf2-IN-10 inhibits oxidative stress by decreasing the levels of MDA, ROS, NQO1 in the liver for gamma-irradiated mice. Keap1-Nrf2-IN-10 improves the survival of gamma-irradiated mice[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
Target	NQO1[1]
References	[1]. Soliman AM, et al. Radiomodulatory effect of a non-electrophilic NQO1 inducer identified in a screen of new 6, 8-diiodoquinazolin-4(3H)-ones carrying a sulfonamide moiety. Eur J Med Chem. 2020 Aug 15;200:112467.

Molecular Formula	C₂₅H₂₂I₂N₄O₇S₂
Molecular Weight	808.40