2648808-69-7
2648808-69-7 structure
- Name: KRAS G12C inhibitor 43
- Chemical Name: KRAS G12C inhibitor 43
- CAS Number: 2648808-69-7
- Molecular Formula: C33H35N7O3
- Molecular Weight: 577.68
- Catalog: Signaling Pathways GPCR/G Protein Ras
- Create Date: 2022-07-02 15:18:59
- Modify Date: 2025-10-02 17:23:43
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KRAS G12C inhibitor 43 (compound 59) is a potent KRAS G12C inhibitor. KRAS G12C inhibitor 43 shows antimigration and anti-proliferative activity with IC50s of 0.001-1 µM, >1 µM, >1 µM for H358, A549, HCC cells ,respectively[1].
| Name | KRAS G12C inhibitor 43 |
|---|
| Description | KRAS G12C inhibitor 43 (compound 59) is a potent KRAS G12C inhibitor. KRAS G12C inhibitor 43 shows antimigration and anti-proliferative activity with IC50s of 0.001-1 µM, >1 µM, >1 µM for H358, A549, HCC cells ,respectively[1]. |
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| Related Catalog | |
| Target |
KRas G12C |
| References |
[1]. Xu Wei, et al. Pyridopyrimidine kras g12c mutant protein inhibitor. WO2021139678A1. |
| Molecular Formula | C33H35N7O3 |
|---|---|
| Molecular Weight | 577.68 |