2416910-88-6

2416910-88-6 structure
2416910-88-6 structure
  • Name: MAO-B-IN-9
  • Chemical Name: MAO-B-IN-9
  • CAS Number: 2416910-88-6
  • Molecular Formula: C18H24N2O2
  • Molecular Weight: 300.40
  • Catalog: Signaling Pathways Neuronal Signaling Monoamine Oxidase
  • Create Date: 2022-07-01 14:37:16
  • Modify Date: 2024-01-02 11:43:44
  • MAO-B-IN-9 (compound 16) is a potent, selective, BBB-penetrated, irreversible and time-dependent MAO-B (monoamine oxidase B) inhibitor, with an IC50 of 0.18 μM. MAO-B-IN-9 prevents Aβ1-42-induced neuronal cell death. MAO-B-IN-9 shows neuroprotective effects, which may be the result of its Aβ1-42 anti-aggregation effects[1].

Name MAO-B-IN-9
Description MAO-B-IN-9 (compound 16) is a potent, selective, BBB-penetrated, irreversible and time-dependent MAO-B (monoamine oxidase B) inhibitor, with an IC50 of 0.18 μM. MAO-B-IN-9 prevents Aβ1-42-induced neuronal cell death. MAO-B-IN-9 shows neuroprotective effects, which may be the result of its Aβ1-42 anti-aggregation effects[1].
Related Catalog
Target

MAO-B:0.178 ± 0. μM (IC50)

References

[1]. Košak U, et al. N-alkylpiperidine carbamates as potential anti-Alzheimer's agents. Eur J Med Chem. 2020 Jul 1;197:112282.

Molecular Formula C18H24N2O2
Molecular Weight 300.40
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.