1004614-86-1

1004614-86-1 structure

Name: mGluR2 modulator 2
Chemical Name: mGluR2 modulator 2
CAS Number: 1004614-86-1
Molecular Formula: C₂₀H₂₂FN₃
Molecular Weight: 323.41
Catalog: Signaling Pathways GPCR/G Protein mGluR
Create Date: 2022-07-10 21:38:15
Modify Date: 2025-09-22 08:54:59
mGluR2 modulator 2 (compound 2) is a potent, selective and orally bioavailable mGluR2 positive allosteric modulator with an EC50 value of 0.13 μM. mGluR2 modulator 2 can be used for researching antipsychotic[1].

Name	mGluR2 modulator 2

Description	mGluR2 modulator 2 (compound 2) is a potent, selective and orally bioavailable mGluR2 positive allosteric modulator with an EC50 value of 0.13 μM. mGluR2 modulator 2 can be used for researching antipsychotic[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
Target	mGluR2:0.13 μM (EC50)
References	[1]. Szabó G, et al. Discovery of dihydropyrazino-benzimidazole derivatives as metabotropic glutamate receptor-2 (mGluR2) positive allosteric modulators (PAMs). Eur J Med Chem. 2020;186:111881.

Molecular Formula	C₂₀H₂₂FN₃
Molecular Weight	323.41