1004614-58-7

1004614-58-7 structure

Name: mGluR2 modulator 3
Chemical Name: mGluR2 modulator 3
CAS Number: 1004614-58-7
Molecular Formula: C₂₁H₂₅N₃O
Molecular Weight: 335.44
Catalog: Signaling Pathways GPCR/G Protein mGluR
Create Date: 2022-07-01 11:40:14
Modify Date: 2025-08-25 19:36:40
mGluR2 modulator 3 (compound 1) is a potent mGluR2 positive allosteric modulator with an EC50 value of 0.87 μM. mGluR2 modulator 3 has activity in psychosis disease models such as methamphetamine-induced hyperactivity and mescaline-induced scratching in mice[1].

Name	mGluR2 modulator 3

Description	mGluR2 modulator 3 (compound 1) is a potent mGluR2 positive allosteric modulator with an EC50 value of 0.87 μM. mGluR2 modulator 3 has activity in psychosis disease models such as methamphetamine-induced hyperactivity and mescaline-induced scratching in mice[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> mGluR Research Areas >> Neurological Disease
Target	mGluR2:0.87 μM (EC50)
References	[1]. Szabó G, et al. Discovery of dihydropyrazino-benzimidazole derivatives as metabotropic glutamate receptor-2 (mGluR2) positive allosteric modulators (PAMs). Eur J Med Chem. 2020;186:111881.

Molecular Formula	C₂₁H₂₅N₃O
Molecular Weight	335.44