302952-43-8

302952-43-8 structure

Name: MRGPRX1 agonist 2
Chemical Name: MRGPRX1 agonist 2
CAS Number: 302952-43-8
Molecular Formula: C₁₅H₁₄N₂OS
Molecular Weight: 270.35
Catalog: Research Areas Neurological Disease
Create Date: 2022-07-06 18:05:26
Modify Date: 2025-08-27 11:40:40
MRGPRX1 agonist 2 (compound 1a) is a potent Mas-related G protein-coupled receptor X1 (MRGPRX1) positive allosteric modulator with an EC50 value of 0.48 μM. MRGPRX1 agonist 2 can be used for researching neuropathic pain[1].

Name	MRGPRX1 agonist 2

Description	MRGPRX1 agonist 2 (compound 1a) is a potent Mas-related G protein-coupled receptor X1 (MRGPRX1) positive allosteric modulator with an EC50 value of 0.48 μM. MRGPRX1 agonist 2 can be used for researching neuropathic pain[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
Target	EC50: 0.48 μM (MRGPRX1)[1]
References	[1]. Berhane I, et al. Thieno[2,3-d]pyrimidine-Based Positive Allosteric Modulators of Human Mas-Related G Protein-Coupled Receptor X1 (MRGPRX1). J Med Chem. 2022;65(4):3218-3228.

Molecular Formula	C₁₅H₁₄N₂OS
Molecular Weight	270.35