2654741-56-5
2654741-56-5 structure
- Name: SOS1-IN-12
- Chemical Name: SOS1-IN-12
- CAS Number: 2654741-56-5
- Molecular Formula: C23H26F3N5
- Molecular Weight: 429.48
- Catalog: Signaling Pathways GPCR/G Protein Ras
- Create Date: 2022-07-28 20:45:35
- Modify Date: 2025-08-27 11:13:45
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SOS1-IN-12 is a potent son of sevenless homolog 1 (SOS1) inhibitor with a Ki of 0.11 nM for SOS1 and an IC50 of 47 nM for pERK. SOS1-IN-13 can be used for researching anticancer[1].
| Name | SOS1-IN-12 |
|---|
| Description | SOS1-IN-12 is a potent son of sevenless homolog 1 (SOS1) inhibitor with a Ki of 0.11 nM for SOS1 and an IC50 of 47 nM for pERK. SOS1-IN-13 can be used for researching anticancer[1]. |
|---|---|
| Related Catalog | |
| Target |
Ki: 0.11 nM (SOS1)[1] IC50: 47 nM (pERK)[1] |
| References |
[1]. Matthew Arnold Marx, et al. Sos1 inhibitors. WO2021127429A1 (compound 6-4) |
| Molecular Formula | C23H26F3N5 |
|---|---|
| Molecular Weight | 429.48 |