2068737-10-8

2068737-10-8 structure

Name: TRAP-6-IN-1
Chemical Name: TRAP-6-IN-1
CAS Number: 2068737-10-8
Molecular Formula: C₁₈H₂₀O₃
Molecular Weight: 284.35
Catalog: Signaling Pathways GPCR/G Protein Protease-Activated Receptor (PAR)
Create Date: 2022-07-10 17:40:17
Modify Date: 2024-09-19 12:23:11
TRAP-6-IN-1 (Compound 8) is a dual collagen and TRAP-6 inhibitor with IC50 values of 17.12 µM and 11.88 µM against collagen and TRAP-6, respectively. TRAP-6-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner[1].

Name	TRAP-6-IN-1

Description	TRAP-6-IN-1 (Compound 8) is a dual collagen and TRAP-6 inhibitor with IC50 values of 17.12 µM and 11.88 µM against collagen and TRAP-6, respectively. TRAP-6-IN-1 inhibits agonist-induced platelet aggregation in a non-competitive manner[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Protease-Activated Receptor (PAR)
Target	IC50: 11.88 µM (TRAP-6), 17.12 µM (collagen)[1]
References	[1]. Méndez D, et al. Synthesis of antiplatelet ortho-carbonyl hydroquinones with differential action on platelet aggregation stimulated by collagen or TRAP-6. Eur J Med Chem. 2020 Apr 15;192:112187.

Molecular Formula	C₁₈H₂₀O₃
Molecular Weight	284.35