298207-49-5

298207-49-5 structure
298207-49-5 structure
  • Name: FLT3-IN-16
  • Chemical Name: N-(3-carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyridine-3-carboxamide
  • CAS Number: 298207-49-5
  • Molecular Formula: C15H15N3O2S
  • Molecular Weight: 301.36
  • Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FLT3
  • Create Date: 2022-07-30 16:30:13
  • Modify Date: 2024-04-07 16:35:23
  • FLT3-IN-16 is a potent FLT3 inhibitor with an IC50 of 1.1 μM. FLT3-IN-16 can be used for researching acute myeloid leukemia[1].

Name N-(3-carbamoyl-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)pyridine-3-carboxamide
Description FLT3-IN-16 is a potent FLT3 inhibitor with an IC50 of 1.1 μM. FLT3-IN-16 can be used for researching acute myeloid leukemia[1].
Related Catalog
Target

IC50: 1.1 μM (FLT3)[1]

In Vitro FLT3-IN-16 (compound 9, 0-10 μM) exhibits anti-proliferative activities against MV4-11 cells with an IC50 value of 2.0 μM[1].
References

[1]. Patch RJ, et, al. Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3282-6.

Density 1.391±0.06 g/cm3(Predicted)
Boiling Point 394.8±42.0 °C(Predicted)
Molecular Formula C15H15N3O2S
Molecular Weight 301.36
Storage condition -20°C