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2332835-02-4

2332835-02-4 structure

2332835-02-4 structure

Name: PSB-1901
Chemical Name: PSB-1901
CAS Number: 2332835-02-4
Molecular Formula: C₂₄H₂₅BrN₆O₄S
Molecular Weight: 573.46
Catalog: Signaling Pathways GPCR/G Protein Adenosine Receptor
Create Date: 2022-08-14 17:39:53
Modify Date: 2026-08-06 10:34:43
PSB-1901 is a potent A2B adenosine receptor (A2BAR) antagonist with Kis of 0.0835 nM and 0.131 nM for human and mouse A2BARs respectively. PSB-1901 can be used for the research of cancer[1].

Name	PSB-1901
Synonyms	1H-Purine-2,6-dione, 8-[4-[[4-(4-bromophenyl)-1-piperazinyl]sulfonyl]phenyl]-3,9-dihydro-1-propyl 8-(4-((4-(4-Bromophenyl)piperazin-1-yl)sulfonyl)phenyl)-1-propyl-3,7-dihydro-1H-purine-2,6-dione PSB-1901 free base

Description	PSB-1901 is a potent A2B adenosine receptor (A2BAR) antagonist with Kis of 0.0835 nM and 0.131 nM for human and mouse A2BARs respectively. PSB-1901 can be used for the research of cancer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor
Target	Ki: 0.0835 nM (human A2BAR), 0.131 nM (mouse A2BAR)[1]
References	[1]. Jiang J, et al. A2B Adenosine Receptor Antagonists with Picomolar Potency. J Med Chem. 2019 Apr 25;62(8):4032-4055.

Molecular Formula	C₂₄H₂₅BrN₆O₄S
Molecular Weight	573.46

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