271579-12-5
271579-12-5 structure
- Name: Thonningianin B
- Chemical Name: Thonningianin B
- CAS Number: 271579-12-5
- Molecular Formula: C35H30O17
- Molecular Weight: 722.60
- Catalog: Signaling Pathways Autophagy Autophagy
- Create Date: 2022-08-22 10:29:01
- Modify Date: 2024-01-09 21:17:49
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Thonningianin B is an antioxidant and an autophagy enhancer[1][2].
| Name | Thonningianin B |
|---|
| Description | Thonningianin B is an antioxidant and an autophagy enhancer[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Thonningianin B 对 DPPH 自由基有较强的清除作用。34.5 μM 的 Thonningianin B 溶液可以完全清除 DPPH 自由基。在另一个实验中，Thonningianin B 的 IC50 值为 21 μM[1]。 Thonningianin B (0-100 μM; 24 h) 抑制 BV-2 细胞活力，IC50 为 46.74 μM[2]。 Thonningianin B (10 μM;24 h) 显著提高了 BV-2 细胞中 LC3-II/LC3-I 的比例和每个细胞平均 GFP-LC3 点数[2]。 Cell Viability Assay[2] Cell Line: BV-2 cells Concentration: 0-100 μM Incubation Time: 24 h Result: Inhibited viability with an IC50 of 46.74 μM. Cell Autophagy Assay[2] Cell Line: BV-2 cells Concentration: 10 μM Incubation Time: 24 h Result: Significantly improved the ratio of LC3-II/LC3-I and the average number of GFP-LC3 puncta per cell. |
| References |
| Molecular Formula | C35H30O17 |
|---|---|
| Molecular Weight | 722.60 |