2242503-82-6

2242503-82-6 structure

2242503-82-6 structure

Name: Anticancer agent 74
Chemical Name: Anticancer agent 74
CAS Number: 2242503-82-6
Molecular Formula: C₂₅H₂₁NO
Molecular Weight: 351.44
Catalog: Research Areas Cancer
Create Date: 2022-08-17 19:20:20
Modify Date: 2024-04-07 16:08:12
Anticancer agent 74 is a moderate anticancer agent. Anticancer agent 74 has lower selectivity and cytotoxicity than doxorubicin to normal cell[1].

Name	Anticancer agent 74

Description	Anticancer agent 74 is a moderate anticancer agent. Anticancer agent 74 has lower selectivity and cytotoxicity than doxorubicin to normal cell[1].
Related Catalog	Research Areas >> Cancer
In Vitro	Anticancer agent 74 has low cytotoxicity in HepG2 (IC50: 72.27 μM), A549 (IC50: 70.79 μM), HuCCA-1 (IC50: 70.42 μM) and MOLT-3 (IC50: 20.71 μM) cell lines. Anticancer agent 74 has low selectivity in HepG2 (IC50: 0.88 μM), A549 (IC50: 5.08 μM), HuCCA-1 (IC50: 5.11 μM) and MOLT-3 (IC50: 17.39 μM) cell lines[1]. Cell Cytotoxicity Assay Cell Line: A549, HuCCA-1, HepG2 and MOLT-3 cell lines Concentration: Incubation Time: Result: Had good cytotoxicity, low selectivity and cytotoxicity in all four primary cancer cell lines.
References	[1]. Bhornrawin Akkachairin, et al. Synthesis of neocryptolepines and carbocycle-fused quinolines and evaluation of their anticancer and antiplasmodial activities, Bioorg Chem. 2020 May;98:103732.

Molecular Formula	C₂₅H₂₁NO
Molecular Weight	351.44