2414491-13-5

2414491-13-5 structure

Name: Anticancer agent 75
Chemical Name: Anticancer agent 75
CAS Number: 2414491-13-5
Molecular Formula: C₂₂H₂₄N₂O
Molecular Weight: 332.44
Catalog: Signaling Pathways Cell Cycle/DNA Damage Topoisomerase
Create Date: 2022-08-05 19:44:22
Modify Date: 2024-01-09 18:43:16
Anticancer agent 75 is a potent anticancer agent. Anticancer agent 75 shows cytotoxicity and selectivity in cancer cell lines. Anticancer agent 75 shows cytotoxicity to normal human kidney cell lines is at least 35 times lower than that of the Doxorubicin standard. Anticancer agent 75 shows good activity of antiplasmodial[1].

Name	Anticancer agent 75

Description	Anticancer agent 75 is a potent anticancer agent. Anticancer agent 75 shows cytotoxicity and selectivity in cancer cell lines. Anticancer agent 75 shows cytotoxicity to normal human kidney cell lines is at least 35 times lower than that of the Doxorubicin standard. Anticancer agent 75 shows good activity of antiplasmodial[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase Research Areas >> Infection
Target	Topoisomerase II
In Vitro	Anticancer agent 75 (Compounds 3h) shows good anticancer activity and at least 35 times less toxic than Doxorubicin[1]. Anticancer agent 75 (Compounds 3h) inhibits cancer cell growth with IC50 values of 333.83 µM, 13.39 µM, 15.31 µM, 15.58 µM, and 4.90 µM for HEK-293, HuCCA-1, A549, HepG2, and MOLT-3, respectively[1].
References	[1]. Bhornrawin Akkachairin, et al. Synthesis of Neocryptolepines and Carbocycle-Fused Quinolines and Evaluation of Their Anticancer and Antiplasmodial Activities. Journal Pre-proofs. 2020, 98: 103732.

Molecular Formula	C₂₂H₂₄N₂O
Molecular Weight	332.44