2402753-39-1

2402753-39-1 structure

Name: BuChE-IN-5
Chemical Name: BuChE-IN-5
CAS Number: 2402753-39-1
Molecular Formula: C₂₅H₃₅N₃
Molecular Weight: 377.57
Catalog: Signaling Pathways Neuronal Signaling AChE
Create Date: 2022-09-02 08:04:27
Modify Date: 2023-03-11 09:06:28
BuChE-IN-5 (compound 25b) is a potent BuChE inhibitor with an IC50 value of 1.94 μM. BuChE-IN-5 efficiently inhibits aggregation Aβ and tau protein in Escherichia coli. BuChE-IN-5 also has free radical scavenging capacity and antioxidant activity. BuChE-IN-5 can be used for researching Alzheimer’s disease[1].

Name	BuChE-IN-5

Description	BuChE-IN-5 (compound 25b) is a potent BuChE inhibitor with an IC50 value of 1.94 μM. BuChE-IN-5 efficiently inhibits aggregation Aβ and tau protein in Escherichia coli. BuChE-IN-5 also has free radical scavenging capacity and antioxidant activity. BuChE-IN-5 can be used for researching Alzheimer’s disease[1].
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> AChE
Target	Butyrylcholinesterase:1.94 μM (IC50)
References	[1]. Wichur T, et al. 1-Benzylpyrrolidine-3-amine-based BuChE inhibitors with anti-aggregating, antioxidant and metal-chelating properties as multifunctional agents against Alzheimer's disease. Eur J Med Chem. 2020 Feb 1;187:111916.

Molecular Formula	C₂₅H₃₅N₃
Molecular Weight	377.57