2459929-62-3

2459929-62-3 structure

Name: HIV-IN-5
Chemical Name: HIV-IN-5
CAS Number: 2459929-62-3
Molecular Formula: C₃₀H₂₄N₂O₈S
Molecular Weight: 572.59
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2022-08-28 18:59:51
Modify Date: 2025-09-05 11:27:47
HIV-IN-5 (compound 5r) is a potent HIV-1 inhibitor, with an IC50 of 0.16 μM. HIV-IN-5 shows inhibition of HIV DNA-dependent DNA polymerization activity, with an IC50 of 2.18 μM. HIV-IN-5 can bind to NNIBP (NNRTIs (non-nucleoside reverse transcriptase inhibitors) binding pocket) [1].

Name	HIV-IN-5

Description	HIV-IN-5 (compound 5r) is a potent HIV-1 inhibitor, with an IC50 of 0.16 μM. HIV-IN-5 shows inhibition of HIV DNA-dependent DNA polymerization activity, with an IC50 of 2.18 μM. HIV-IN-5 can bind to NNIBP (NNRTIs (non-nucleoside reverse transcriptase inhibitors) binding pocket) [1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
Target	HIV-1:0.16 ± 0.0 μM (IC50) HIV-1 (Y181C):>100 μM (IC50) HIV-1 (K103N):>100 μM (IC50)
References	[1]. Yi-MingLi, et al. Design, synthesis and anti-HIV evaluation of 5-alkyl- 6-(benzo[d][1,3]dioxol-5-alkyl)-2-mercaptopyrimidin-4(3H)-ones as potent HIV-1 NNRTIs. September 2020;102:104041.

Molecular Formula	C₃₀H₂₄N₂O₈S
Molecular Weight	572.59