1351337-07-9

1351337-07-9 structure

Name: Obiltoxaximab
Chemical Name: Obiltoxaximab
CAS Number: 1351337-07-9
Molecular Formula:
Molecular Weight:
Catalog: Research Areas Infection
Create Date: 2022-08-12 21:06:25
Modify Date: 2024-09-13 18:48:16
Obiltoxaximab is a potent anti-protective antigen (PA) monoclonal antibody. Obiltoxaximab plays a central role in anthrax toxin assembly and target cell intoxication. Obiltoxaximab can be used in animal‐to‐human dose translation for treatment of inhalational anthrax[1][2].

Name	Obiltoxaximab

Description	Obiltoxaximab is a potent anti-protective antigen (PA) monoclonal antibody. Obiltoxaximab plays a central role in anthrax toxin assembly and target cell intoxication. Obiltoxaximab can be used in animal‐to‐human dose translation for treatment of inhalational anthrax[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Others >> Others
References	[1]. Nagy CF, et al. Animal-to-Human Dose Translation of Obiltoxaximab for Treatment of Inhalational Anthrax Under the US FDA Animal Rule. Clin Transl Sci. 2017 Jan;10(1):12-19. [2]. Yamamoto BJ, et al. Obiltoxaximab Prevents Disseminated Bacillus anthracis Infection and Improves Survival during Pre- and Postexposure Prophylaxis in Animal Models of Inhalational Anthrax. Antimicrob Agents Chemother. 2016 Sep 23;60(10):5796-805.

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