519021-48-8

519021-48-8 structure
519021-48-8 structure
  • Name: pUL89 Endonuclease-IN-2
  • Chemical Name: pUL89 Endonuclease-IN-2
  • CAS Number: 519021-48-8
  • Molecular Formula: C17H12F3N3O3S
  • Molecular Weight: 395.36
  • Catalog: Signaling Pathways Anti-infection CMV
  • Create Date: 2022-08-05 10:34:49
  • Modify Date: 2025-08-27 18:45:59
  • pUL89 Endonuclease-IN-2 (Compound 15k) is a potent inhibitor of human cytomegalovirus (HCMV) pUL89 endonuclease with the IC50 of 3.0 μM. Antiviral activities[1].

Name pUL89 Endonuclease-IN-2
Description pUL89 Endonuclease-IN-2 (Compound 15k) is a potent inhibitor of human cytomegalovirus (HCMV) pUL89 endonuclease with the IC50 of 3.0 μM. Antiviral activities[1].
Related Catalog
In Vitro Cell Viability Assay Cell Line: HFF cells Concentration: 10 μM Incubation Time: 168 hours Result: Inhibited HCMV replication in HFF cell with the EC50 value of 14.4 μM.
References

[1]. Tianyu He, et al. 4,5-Dihydroxypyrimidine Methyl Carboxylates, Carboxylic Acids, and Carboxamides as Inhibitors of Human Cytomegalovirus pUL89 Endonuclease. J Med Chem. 2022 Apr 14;65(7):5830-5849.

Molecular Formula C17H12F3N3O3S
Molecular Weight 395.36
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