2712534-78-4

2712534-78-4 structure

Name: PXYD4
Chemical Name: PXYD4
CAS Number: 2712534-78-4
Molecular Formula: C₂₅H₂₁NO₅
Molecular Weight: 415.44
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2022-08-31 06:16:08
Modify Date: 2024-09-10 19:41:16
PXYD4 is a ribosomal protein S1 (RpsA) antagonist with Kds of 3.24 and 1.64 μM for RpsA-CTD and RpsA-CTD Δ438A, respectively. RpsA plays an important role in the trans-translation process of Mycobacterium Tuberculosis (Mtb)[1].

Name	PXYD4

Description	PXYD4 is a ribosomal protein S1 (RpsA) antagonist with Kds of 3.24 and 1.64 μM for RpsA-CTD and RpsA-CTD Δ438A, respectively. RpsA plays an important role in the trans-translation process of Mycobacterium Tuberculosis (Mtb)[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	Kd: 3.24 μM (RpsA)[1]
In Vitro	PXYD4 has high affinity for both RpsA-CTD (WT) and RpsA-CTD △438A (Mutant) with Kd values of 3.24 μM and 1.64 μM, respectively[1].
References	[1]. Yazhuang Dai, et al. Discovery and evaluation of new compounds targeting ribosomal protein S1 in antibiotic-resistant Mycobacterium Tuberculosis. Eur J Med Chem. 2020 Jun 15;196:112317.

Molecular Formula	C₂₅H₂₁NO₅
Molecular Weight	415.44