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2616821-92-0

2616821-92-0 structure

2616821-92-0 structure

Name: (S)-PERK-IN-5
Chemical Name: (S)-PERK-IN-5
CAS Number: 2616821-92-0
Molecular Formula: C₂₅H₂₆F₂N₄O₃
Molecular Weight: 468.50
Catalog: Signaling Pathways Cell Cycle/DNA Damage PERK
Create Date: 2022-08-14 16:08:50
Modify Date: 2024-01-08 15:08:32
(S)-PERK-IN-5 is the S-enantiomer of PERK-IN-5. (S)-PERK-IN-5 (example 39) is a PERK inhibitor, with an IC50 of 0.101-0.250 μM[1][2].

Name	(S)-PERK-IN-5

Description	(S)-PERK-IN-5 is the S-enantiomer of PERK-IN-5. (S)-PERK-IN-5 (example 39) is a PERK inhibitor, with an IC50 of 0.101-0.250 μM[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> PERK
References	[1]. Calvo V, et al. Discovery of 2-amino-3-amido-5-aryl-pyridines as highly potent, orally bioavailable, and efficacious PERK kinase inhibitors. Bioorg Med Chem Lett. 2021;43:128058. [2]. Alan C. Rigby, et al. Perk inhibitors for treating viral infections. WO2021231782A1.

Molecular Formula	C₂₅H₂₆F₂N₄O₃
Molecular Weight	468.50

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