1826337-40-9

1826337-40-9 structure
1826337-40-9 structure
  • Name: S07-2005 (racemic)
  • Chemical Name: S07-2005 (racemic)
  • CAS Number: 1826337-40-9
  • Molecular Formula: C20H23NO6
  • Molecular Weight: 373.40
  • Catalog: Research Areas Cancer
  • Create Date: 2022-08-18 11:04:24
  • Modify Date: 2024-09-14 11:40:37
  • S07-2005 racemic is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 value of 0.13 μM and 0.75 μM for AKR1C3 and AKR1C4, respectively. S07-2005 racemic has potential as a chemotherapeutic potentiator for cancer drug resistance[1].

Name S07-2005 (racemic)
Description S07-2005 racemic is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 value of 0.13 μM and 0.75 μM for AKR1C3 and AKR1C4, respectively. S07-2005 racemic has potential as a chemotherapeutic potentiator for cancer drug resistance[1].
Related Catalog
Target

IC50: 2.88 ± 1.10 μM (AKR1C1), 0.13 ± 0.03 μM (AKR1C3), 0.75 ± 0.32 μM (AKR1C4)[1]

References

[1]. Siyu He, et al. Discovery of Novel Aldo-Keto Reductase 1C3 Inhibitors as Chemotherapeutic Potentiators for Cancer Drug Resistance. ACS Med. Chem. Lett. Jun 2022.

Molecular Formula C20H23NO6
Molecular Weight 373.40