1826337-40-9

1826337-40-9 structure

Name: S07-2005 (racemic)
Chemical Name: S07-2005 (racemic)
CAS Number: 1826337-40-9
Molecular Formula: C₂₀H₂₃NO₆
Molecular Weight: 373.40
Catalog: Research Areas Cancer
Create Date: 2022-08-18 11:04:24
Modify Date: 2024-09-14 11:40:37
S07-2005 racemic is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 value of 0.13 μM and 0.75 μM for AKR1C3 and AKR1C4, respectively. S07-2005 racemic has potential as a chemotherapeutic potentiator for cancer drug resistance[1].

Name	S07-2005 (racemic)

Description	S07-2005 racemic is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 value of 0.13 μM and 0.75 μM for AKR1C3 and AKR1C4, respectively. S07-2005 racemic has potential as a chemotherapeutic potentiator for cancer drug resistance[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	IC50: 2.88 ± 1.10 μM (AKR1C1), 0.13 ± 0.03 μM (AKR1C3), 0.75 ± 0.32 μM (AKR1C4)[1]
References	[1]. Siyu He, et al. Discovery of Novel Aldo-Keto Reductase 1C3 Inhibitors as Chemotherapeutic Potentiators for Cancer Drug Resistance. ACS Med. Chem. Lett. Jun 2022.

Molecular Formula	C₂₀H₂₃NO₆
Molecular Weight	373.40