1594427-18-5

1594427-18-5 structure

Name: Viral 2C protein inhibitor 1
Chemical Name: Viral 2C protein inhibitor 1
CAS Number: 1594427-18-5
Molecular Formula: C₁₉H₁₈FN₃O
Molecular Weight: 323.36
Catalog: Research Areas Infection
Create Date: 2022-09-18 13:03:38
Modify Date: 2024-04-11 19:29:16
Viral 2C protein inhibitor 1 (compound 6aw) is a potent and broad-spectrum enterovirus antiviral agent, inhibiting viral 2C protein. Viral 2C protein inhibitor 1 inhibits multiple strains of EV-D68, EV-A71 and CVB3 with EC50s of 0.1~3.6 µM, and exhibits high selectivity index and relatively low cytotoxicity[1].

Name	Viral 2C protein inhibitor 1

Description	Viral 2C protein inhibitor 1 (compound 6aw) is a potent and broad-spectrum enterovirus antiviral agent, inhibiting viral 2C protein. Viral 2C protein inhibitor 1 inhibits multiple strains of EV-D68, EV-A71 and CVB3 with EC50s of 0.1~3.6 µM, and exhibits high selectivity index and relatively low cytotoxicity[1].
Related Catalog	Research Areas >> Infection
Target	EC50: 0.1~0.2 µM (EV-D68), 3.1 µM (EV-A71), 0.2 µM (CVB3)[1]
References	[1]. Musharrafieh R, et al. Development of broad-spectrum enterovirus antivirals based on quinoline scaffold. Bioorg Chem. 2020 Aug;101:103981.

Molecular Formula	C₁₉H₁₈FN₃O
Molecular Weight	323.36