736154-60-2
736154-60-2 structure
- Name: Schnurri-3 inhibitor-1
- Chemical Name: Benzenesulfonamide, 3,4-difluoro-N-(4-pyridinylmethyl)-
- CAS Number: 736154-60-2
- Molecular Formula: C12H10F2N2O2S
- Molecular Weight: 284.28
- Catalog: Research Areas Others
- Create Date: 2022-09-30 15:31:56
- Modify Date: 2024-04-08 16:40:48
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Schnurri-3 inhibitor-1 is a potent schnurri-3 inhibitor which is an essential regulator of adult bone formation. Schnurri-3 inhibitor-1 can inhibit Shn3 with EF1alpha promoter in osteoblast cell line Shn3FFL with an AC50 value of 2.09 μM. Schnurri-3 inhibitor-1 can be used to research osteoporosis[1].
| Name | Benzenesulfonamide, 3,4-difluoro-N-(4-pyridinylmethyl)- |
|---|
| Description | Schnurri-3 inhibitor-1 is a potent schnurri-3 inhibitor which is an essential regulator of adult bone formation. Schnurri-3 inhibitor-1 can inhibit Shn3 with EF1alpha promoter in osteoblast cell line Shn3FFL with an AC50 value of 2.09 μM. Schnurri-3 inhibitor-1 can be used to research osteoporosis[1]. |
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| Related Catalog | |
| Target |
Schnurri-3[1] |
| In Vitro | Schnurri-3 inhibitor-1 (0-50 μM; 24 h) can inhibit Shn3 with EF1alpha promoter in SV40 large T antigen-transformed osteoblast cell line (Clone20-Shn3FFL) with an AC50 value of 2.09 μM[1]. Schnurri-3 inhibitor-1 (0.195-26 μM; 48 h) exhibits moderate activity in HepG2 mammalian cells with an AC50 value of 54.73 μM[1]. Cell Viability Assay[1] Cell Line: Clone20-Shn3FFL cells Concentration: 2.09 μM Incubation Time: 24 hours Result: Showed the active concentration AC50 value of 2.09 μM. Cell Viability Assay[1] Cell Line: Clone20-Shn3FFL cells Concentration: 1.2 μM Incubation Time: 24 hours Result: Showed the active concentration AC50 value of 1.2 μM. |
| References |
[1]. National Center for Biotechnology Information. PubChem Compound Summary for CID 2473445. |
| Molecular Formula | C12H10F2N2O2S |
|---|---|
| Molecular Weight | 284.28 |