107648-79-3
107648-79-3 structure
- Name: Cefepime chloride
- Chemical Name: Cefepime chloride
- CAS Number: 107648-79-3
- Molecular Formula: C19H25ClN6O5S2
- Molecular Weight: 517.02
- Catalog: Research Areas Infection
- Create Date: 2022-09-16 18:49:14
- Modify Date: 2023-02-03 19:52:00
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Cefepime (BMY-28142) chloride is a broad-spectrum and cross the blood-brain barrier cephalosporin. Cefepime chloride shows antibacterial effects against both Gram-positive and Gram-negative aerobic bacteria. Cefepime chloride induces neurotoxicity[1][2][3][4].
| Name | Cefepime chloride |
|---|
| Description | Cefepime (BMY-28142) chloride is a broad-spectrum and cross the blood-brain barrier cephalosporin. Cefepime chloride shows antibacterial effects against both Gram-positive and Gram-negative aerobic bacteria. Cefepime chloride induces neurotoxicity[1][2][3][4]. |
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| Related Catalog | |
| In Vitro | Cefepime chloride exerts its antibacterial effects by binding to penicillin-binding proteins[2]. |
| In Vivo | Cefepime chloride (80 mg/kg; i.p.) significantly increases the half-life and mice surviveed[4]. Animal Model: Male CD-1 mice[4] Dosage: 80 mg/kg Administration: I.p. Result: Significantly prolonged the half-life of cefepime and all mice survived at 18-22 mg/kg cisplatin, and when pretreatment with 26 mg/kg cisplatin significantly decreased survival with the half-life of cefepime was not significantly longer than of 18 mg/kg cisplatin. |
| References |
| Molecular Formula | C19H25ClN6O5S2 |
|---|---|
| Molecular Weight | 517.02 |