Shanghai Nianxing Industrial Co., Ltd
China
Product Name: DENV-IN-5
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Purity: 98.39%
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2375781-06-7

2375781-06-7 structure

2375781-06-7 structure

Name: DENV-IN-5
Chemical Name: DENV-IN-5
CAS Number: 2375781-06-7
Molecular Formula: C₂₃H₂₅ClF₂N₄OS
Molecular Weight: 478.99
Catalog: Signaling Pathways Anti-infection HIV
Create Date: 2022-09-27 15:22:25
Modify Date: 2024-04-06 18:19:03
DENV-IN-5 (Compound 4b) is a dengue virus (DENV) inhibitor with EC50s of 1.47, 9.23, 7.08 and 8.91 μM against DENV-I ∼ IV replication, respectively. DENV-IN-5 also inhibits HIV-1IIIB strain with an EC50 of 0.1512 μM[1].

Name	DENV-IN-5

Description	DENV-IN-5 (Compound 4b) is a dengue virus (DENV) inhibitor with EC50s of 1.47, 9.23, 7.08 and 8.91 μM against DENV-I ∼ IV replication, respectively. DENV-IN-5 also inhibits HIV-1IIIB strain with an EC50 of 0.1512 μM[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis
Target	HIV (IIIB):0.1512 μM (EC50) DENV-I:1.47 μM (EC50) DENV-II:9.23 μM (EC50) DENV-III:7.08 μM (EC50) DENV-IV:8.91 μM (EC50)
References	[1]. Rui RM, et al. C6-structural optimizations of 2-aryl-1H-pyrazole-S-DABOs: From anti-HIV to anti-DENV activity. Bioorg Chem. 2022 Feb;119:105494.

Molecular Formula	C₂₃H₂₅ClF₂N₄OS
Molecular Weight	478.99

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