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691869-12-2

691869-12-2 structure

691869-12-2 structure

Name: EP4 receptor antagonist 4
Chemical Name: EP4 receptor antagonist 4
CAS Number: 691869-12-2
Molecular Formula: C₁₉H₁₄N₂OS
Molecular Weight: 318.39
Catalog: Signaling Pathways GPCR/G Protein Prostaglandin Receptor
Create Date: 2022-10-06 14:59:18
Modify Date: 2024-09-18 08:19:05
EP4 receptor antagonist 4 is an EP4 receptor agonist with the human pEC50 value of 6.3[1].

Name	EP4 receptor antagonist 4

Description	EP4 receptor antagonist 4 is an EP4 receptor agonist with the human pEC50 value of 6.3[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor
Target	EP4:6.3 (pEC50)
In Vitro	EP4 receptor antagonist 4 (24 h) treatment shows agonism in HEK293 cells stably transfected with hEP4[1]. EP4 receptor antagonist 4 (30 min) treatment shows agonism (pEC50<5) and antagonism (pIC50<5)[1]. Cell Viability Assay[1] Cell Line: HEK293 cells Concentration: Incubation Time: 24 hours Result: Exhibited the human pEC50 value of 6.3.
References	[1]. Joannes Theodorus Maria Linders, et al. Bicyclic derivatives as ep4 agonists. WO2008092860A1

Molecular Formula	C₁₉H₁₄N₂OS
Molecular Weight	318.39

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