Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Sulbentine
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Sulbentine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2H-1,3,5-Thiadiazine-2-thione,tetrahydro-3,5-bis(phenylmethyl)-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

350-12-9

350-12-9 structure

350-12-9 structure

Name: Sulbentine
Chemical Name: 3,5-dibenzyl-1,3,5-thiadiazinane-2-thione
CAS Number: 350-12-9
Molecular Formula: C₁₇H₁₈N₂S₂
Molecular Weight: 314.46800
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2018-09-29 12:49:34
Modify Date: 2025-08-24 19:10:12
Sulbentine is an antifungal.

Name	3,5-dibenzyl-1,3,5-thiadiazinane-2-thione
Synonyms	Noticin Refungine Fungiplex Sulbentine Afungin 3-benzyl-5-phenethyltetrahydro-2H-1,3,5-thiadiazine-2-thione Dibenzthione Dibenzthion 3,5-Dibenzyl-tetrahydro-<1,3,5>thiadiazin-2-thion Carbothialdine 3,5-dibenzyl-3,4,5,6-tetrahydro-2H-1,3,5-thiadiazine-2-thione Mecal Dibenzothione

Description	Sulbentine is an antifungal.
Related Catalog	Signaling Pathways >> Anti-infection >> Fungal Research Areas >> Infection
References	[1]. Thoma K, et al. The photostability of antimycotics. 3. Photostability of locally acting antimycotics. Pharmazie. 1997 May;52(5):362-73. [2]. Hänel H, et al. Evaluation of fungicidal action in vitro and in a skin model considering the influence of penetration kinetics of various standard antimycotics. Ann N Y Acad Sci. 1988;544:329-37.

Density	1.28g/cm3
Boiling Point	451.5ºC at 760mmHg
Molecular Formula	C₁₇H₁₈N₂S₂
Molecular Weight	314.46800
Flash Point	226.9ºC
Exact Mass	314.09100
PSA	63.87000
LogP	3.81330
Index of Refraction	1.705
Storage condition	2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XI2772000

CHEMICAL NAME :: 2H-1,3,5-Thiadiazine-2-thione, tetrahydro-3,5-dibenzyl-

CAS REGISTRY NUMBER :: 350-12-9

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C17-H18-N2-S2

MOLECULAR WEIGHT :: 314.49

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 19,558,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 13,574,1964

HS Code	2934999090

75-15-0 structure

75-15-0

50-00-0 structure

50-00-0

100-46-9 structure

100-46-9

~76%

350-12-9 structure

350-12-9

Literature: Alfaro-Lopez, Josue; Okayama, Toru; Hosohata, Keiko; Davis, Peg; Porreca, Frank; Yamamura, Henry I.; Hruby, Victor J. Journal of Medicinal Chemistry, 1999 , vol. 42, # 26 p. 5359 - 5368

50-00-0 structure

50-00-0

1950-25-0 structure

1950-25-0

100-46-9 structure

100-46-9

~%

350-12-9 structure

350-12-9

Literature: El-Shorbagi, A-Na European Journal of Medicinal Chemistry, 1994 , vol. 29, # 1 p. 11 - 16

Precursor 3
75-15-0 50-00-0 100-46-9
DownStream 1
622-78-6

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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