1257641-15-8

1257641-15-8 structure
1257641-15-8 structure
  • Name: PPARδ/γ agonist 1
  • Chemical Name: PPARδ/γ agonist 1
  • CAS Number: 1257641-15-8
  • Molecular Formula: C25H27NO5
  • Molecular Weight: 421.49
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage PPAR
  • Create Date: 2022-09-11 13:42:52
  • Modify Date: 2025-08-25 15:08:31
  • DB-959 (T3D-959 (free base)) is a potent dual PPAR delta/gamma inhibitor. DB-959 can be used for Alzheimer’s disease research[1].

Name PPARδ/γ agonist 1
Description DB-959 (T3D-959 (free base)) is a potent dual PPAR delta/gamma inhibitor. DB-959 can be used for Alzheimer’s disease research[1].
Related Catalog
In Vivo DB-959 (T3D-959 (free base)) (1 mg/kg; i.g.; daily, for 16 days; STZ-mediated Long Evans rats) restores STZ-mediated impairments of motor function[1]. Animal Model: STZ-mediated Long Evans rats[1] Dosage: 1 mg/kg Administration: Oral gavage; daily, for 16 days Result: Improved performance in the STZ-mediated rats and had neuroprotective for both granule and Purkinje cells.
References

[1]. Tong M, et, al. T3D-959: A Multi-Faceted Disease Remedial Drug Candidate for the Treatment of Alzheimer's Disease. J Alzheimers Dis. 2016;51(1):123-38.

Molecular Formula C25H27NO5
Molecular Weight 421.49
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