1418026-92-2

1418026-92-2 structure

Name: Unecritinib
Chemical Name: Unecritinib
CAS Number: 1418026-92-2
Molecular Formula: C₂₃H₂₄Cl₂FN₅O₂
Molecular Weight: 492.37
Catalog: Signaling Pathways JAK/STAT Signaling EGFR
Create Date: 2022-09-01 15:32:43
Modify Date: 2024-04-05 20:02:35
Unecritinib (TQ-B3101) is a potent EGFR tyrosine kinase inhibitor. Unecritinib shows anticancer activity. Unecritinib inhibits ALK, ROS1, and MET. Unecritinib has the potential for the research of solid tumor and relapsed or refractory ALK-positive anaplastic large cell lymphoma[1][2].

Name	Unecritinib

Description	Unecritinib (TQ-B3101) is a potent EGFR tyrosine kinase inhibitor. Unecritinib shows anticancer activity. Unecritinib inhibits ALK, ROS1, and MET. Unecritinib has the potential for the research of solid tumor and relapsed or refractory ALK-positive anaplastic large cell lymphoma[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR
References	[1]. Yang F, et al. Population Pharmacokinetic Modeling and Simulation of TQ-B3101 to Inform Dosing in Pediatric Patients With Solid Tumors. Front Pharmacol. 2022 Jan 18;12:782518. [2]. Majeed U, et al. Targeted therapy in advanced non-small cell lung cancer: current advances and future trends. J Hematol Oncol. 2021 Jul 8;14(1):108.

Molecular Formula	C₂₃H₂₄Cl₂FN₅O₂
Molecular Weight	492.37