1145663-09-7

1145663-09-7 structure

Name: trans-1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
Chemical Name: rel-Boc-Hyp-OMe
CAS Number: 1145663-09-7
Molecular Formula: C₁₁H₁₉NO₅
Molecular Weight: 245.27
Catalog: Research Areas Cancer
Create Date: 2022-09-22 20:37:32
Modify Date: 2024-04-03 10:51:26
rel-Boc-Hyp-OMe is the inactive isomer of Boc-Hyp-OMe (HY-65039), and can be used as an experimental control. Boc-Hyp-OMe is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-Hyp-OMe is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2].

Name	rel-Boc-Hyp-OMe

Description	rel-Boc-Hyp-OMe is the inactive isomer of Boc-Hyp-OMe (HY-65039), and can be used as an experimental control. Boc-Hyp-OMe is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-Hyp-OMe is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337. [2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Molecular Formula	C₁₁H₁₉NO₅
Molecular Weight	245.27