216571-88-9

216571-88-9 structure

Name: BODIPY FL Verapamil hydrochloride
Chemical Name: BODIPY FL Verapamil hydrochloride
CAS Number: 216571-88-9
Molecular Formula: C₄₁H₅₆BClF₂N₄O₅
Molecular Weight: 769.17
Catalog: Research Areas Others
Create Date: 2022-11-21 16:12:35
Modify Date: 2024-01-10 21:01:56
BODIPY FL Verapamil hydrochloride is a fluorescent dye, it can be used as a molecular probe to label tissues and cells. BODIPY FL Verapamil hydrochloride is a substrate for both ABCB1 and ABCC1[1][2].

Name	BODIPY FL Verapamil hydrochloride

Description	BODIPY FL Verapamil hydrochloride is a fluorescent dye, it can be used as a molecular probe to label tissues and cells. BODIPY FL Verapamil hydrochloride is a substrate for both ABCB1 and ABCC1[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	BODIPY FL Verapamil hydrochloride (10 μM) can be incubated with removed tissue in phosphate buffered solution to demonstrate binding site[1]. BODIPY FL Verapamil hydrochloride (0-100 nM) inhibits ABCB1 and ABCC1 efflux with loxapine, mometasone, nicardipine, pimozide and verapamil with IC50 values of 1.6-15.6 nM[2].
References	[1]. Just S, et al. Histological demonstration of voltage dependent calcium channels on calcitonin gene-related peptide-immunoreactive nerve fibres in the mouse knee joint. Neurosci Lett. 2001 Oct 26;312(3):133-6. [2]. Strouse JJ, et al. Fluorescent substrates for flow cytometric evaluation of efflux inhibition in ABCB1, ABCC1, and ABCG2 transporters. Anal Biochem. 2013 Jun 1;437(1):77-87.

Molecular Formula	C₄₁H₅₆BClF₂N₄O₅
Molecular Weight	769.17