86582-98-1

86582-98-1 structure

Name	N-Acetylneuraminic acid-d3

Description	N-Acetylneuraminic acid-d3 is the deuterium labeled N-Acetylneuraminic acid.
Related Catalog	Signaling Pathways >> Anti-infection >> Influenza Virus Research Areas >> Cardiovascular Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Bondioli L et al. PLGA nanoparticles surface decorated with the sialic acid, N-acetylneuraminic acid. Biomaterials. 2010 Apr;31(12):3395-403.;Kiefel MJ, et al. Synthesis and biological evaluation of N-acetylneuraminic acid-based rotavirus inhibitors. J Me

Molecular Formula	C₁₁H₁₆D₃NO₉
Molecular Weight	312.29