1329802-47-2

1329802-47-2 structure

Name: Silibinin-d5
Chemical Name: Silibinin-d5
CAS Number: 1329802-47-2
Molecular Formula: C₂₅H₁₇D₅O₁₀
Molecular Weight: 487.47
Catalog: Signaling Pathways Autophagy Autophagy
Create Date: 2022-10-11 19:07:36
Modify Date: 2024-01-11 23:40:24
Silibinin-d5 is the deuterium labeled Silibinin. Silibinin (Silibinin A), an effective anti-cancer and chemopreventive agent, has been shown to exert multiple effects on cancer cells, including inhibition of both cell proliferation and migration.

Name	Silibinin-d5

Description	Silibinin-d5 is the deuterium labeled Silibinin. Silibinin (Silibinin A), an effective anti-cancer and chemopreventive agent, has been shown to exert multiple effects on cancer cells, including inhibition of both cell proliferation and migration.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Autophagy >> Autophagy
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Woo SM, et al. Silibinin induces apoptosis of HT29 colon carcinoma cells through early growth response-1 (EGR-1)-mediated non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) up-regulation. Chem Biol Interact. 2014 Jan 16;211C:36-43.;Kim TH, et a

Molecular Formula	C₂₅H₁₇D₅O₁₀
Molecular Weight	487.47