476319-66-1
476319-66-1 structure
- Name: Antimycobacterial agent-4
- Chemical Name: way-658650
- CAS Number: 476319-66-1
- Molecular Formula: C15H10N4O3S
- Molecular Weight: 326.33
- Catalog: Signaling Pathways Anti-infection Bacterial
- Create Date: 2022-10-27 22:29:40
- Modify Date: 2024-04-06 17:15:45
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Antimycobacterial agent-4 is a 2-amino-4-(2-pyridyl) thiazole derivative, with antimycobacterial activity, antiplasmodial activity, and cytotoxicity on a mammalian cell line[1][2].
| Name | way-658650 |
|---|
| Description | Antimycobacterial agent-4 is a 2-amino-4-(2-pyridyl) thiazole derivative, with antimycobacterial activity, antiplasmodial activity, and cytotoxicity on a mammalian cell line[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Antimycobacterial agent-4 (compound 12) exerts antimycobacterial activity against the Mycobacterium tuberculosis H37Rv strain (MIC99=5 μM), and antiplasmodial activity against the Chloroquine (HY-17589A) sensitive NF54 Plasmodium falciparum strain (IC50=6.1 μM) and cytotoxicity on a mammalian cell line (CHO, IC50=2.2 μM)[1]. Antimycobacterial agent-4 (compound 38) shows cytotoxicity against Vero cells with toxic concentration TC50 of 3.0 μM[2]. |
| Molecular Formula | C15H10N4O3S |
|---|---|
| Molecular Weight | 326.33 |