1372645-37-8
1372645-37-8 structure
- Name: Otlertuzumab
- Chemical Name: Otlertuzumab
- CAS Number: 1372645-37-8
- Molecular Formula:
- Molecular Weight:
- Catalog: Research Areas Cancer
- Create Date: 2022-11-22 11:25:14
- Modify Date: 2024-01-19 19:31:30
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Otlertuzumab (TRU-016) is a humanized anti-CD37 monoclonal antibody that can be used for cancer research[1].
| Name | Otlertuzumab |
|---|
| Description | Otlertuzumab (TRU-016) is a humanized anti-CD37 monoclonal antibody that can be used for cancer research[1]. |
|---|---|
| Related Catalog | |
| Target |
CD37[1] |
| In Vitro | Otlertuzumab (TRU-016) in combination with Rituximab (HY-P9913), Rapamycin (HY-10219), or Bendamustine (HY-13567) increases cell killing of NHL cells[2]. Otlertuzumab has the ability to bind to and kill CD37+ cells[3]. |
| In Vivo | Otlertuzumab (TRU-016) in combination with Bendamustine (HY-13567) displays greater anti-tumor activity than either agent alone against a follicular lymphoma tumor model in SCID mice[2]. Otlertuzumab shows significant antitumor activity in mice bearing Ramos or Daudi tumor xenografts[3]. |
| No Any Chemical & Physical Properties |