1227692-67-2

1227692-67-2 structure
1227692-67-2 structure
  • Name: CMB-087229
  • Chemical Name: 5-((3,5-Dichlorophenoxy)methyl)-1,2-dihydro-3H-pyrazol-3-one
  • CAS Number: 1227692-67-2
  • Molecular Formula: C10H8Cl2N2O2
  • Molecular Weight: 259.09
  • Create Date: 2022-11-22 13:03:46
  • Modify Date: 2025-09-01 18:57:35
  • CMB-087229 is a mutant superoxide dismutase 1 (SOD1) protein aggregation inhibitor with IC50 of 67 nM, which can be used in the research of amyotrophic lateral sclerosis[1].

Name 5-((3,5-Dichlorophenoxy)methyl)-1,2-dihydro-3H-pyrazol-3-one
Synonyms MFCD31745789
Description CMB-087229 is a mutant superoxide dismutase 1 (SOD1) protein aggregation inhibitor with IC50 of 67 nM, which can be used in the research of amyotrophic lateral sclerosis[1].
Related Catalog
References

[1]. Tian Chen, et al. ADME-Guided Design and Synthesis of Aryloxanyl Pyrazolone Derivatives To Block Mutant Superoxide Dismutase 1 (SOD1) Cytotoxicity and Protein Aggregation: Potential Application for the Treatment of Amyotrophic Lateral Sclerosis.J. Med. Chem. 2012, 55, 1, 515–527.

Molecular Formula C10H8Cl2N2O2
Molecular Weight 259.09
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