1884577-99-4

1884577-99-4 structure

Name: Boc-Val-Ala-PAB
Chemical Name: tert-Butyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate
CAS Number: 1884577-99-4
Molecular Formula: C₂₀H₃₁N₃O₅
Molecular Weight: 393.48
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2022-11-22 12:02:53
Modify Date: 2024-04-02 17:19:59
Boc-Val-Ala-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate (ADCs)[1][2].

Name	tert-Butyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate
Synonyms	MFCD28557280

Description	Boc-Val-Ala-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate (ADCs)[1][2].
Related Catalog	Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker Research Areas >> Others
References	[1]. HP Wilson, et al. Pyrrolobenzodiazepines and conjugates thereof: World Intellectual Property Organization, WO2016037644. 2016-03-17. [2]. HP Wilson, et al. Preparation of pyrrolobenzodiazepine dimers and their conjugates with cell binding agents, especially pyrrolobenzodiazepine dimer drug linker antibody conjugates and their use for treating proliferative diseases, particularly cancer: World Intellectual Property Organization, WO2016038383. 2016-03-17

Molecular Formula	C₂₀H₃₁N₃O₅
Molecular Weight	393.48