298207-77-9

298207-77-9 structure
298207-77-9 structure
  • Name: VEGFR-2-IN-37
  • Chemical Name: WAY-357919
  • CAS Number: 298207-77-9
  • Molecular Formula: C18H16N2O2S
  • Molecular Weight: 324.40
  • Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK VEGFR
  • Create Date: 2023-01-19 15:46:12
  • Modify Date: 2024-04-06 07:18:16
  • VEGFR-2-IN-37 (compound 12) is an inhibitor of VEGFR-2. The inhibition rate at 200 μM was approximately 56.9 μM. VEGFR-2-IN-37 is a potential inhibitor of human umbilical vein endothelial cell (HUVEC) proliferation[1].

Name WAY-357919
Synonyms 3'-[(5,6,7,8-Tetrahydro[1]benzothieno[2,3-d]pyrimidine-4-yl)oxy]acetophenone
Description VEGFR-2-IN-37 (compound 12) is an inhibitor of VEGFR-2. The inhibition rate at 200 μM was approximately 56.9 μM. VEGFR-2-IN-37 is a potential inhibitor of human umbilical vein endothelial cell (HUVEC) proliferation[1].
Related Catalog
Target

VEGFR-2[1]

References

[1]. Perspicace E, et al. Design, synthesis and biological evaluation of new classes of thieno[3,2-d]pyrimidinone and thieno[1,2,3]triazine as inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2). Eur J Med Chem. 2013 May;63:765-81.  

Molecular Formula C18H16N2O2S
Molecular Weight 324.40
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