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5531-98-6

5531-98-6 structure
5531-98-6 structure
  • Name: Atherosperminine
  • Chemical Name: Atherosperminine
  • CAS Number: 5531-98-6
  • Molecular Formula: C20H23NO2
  • Molecular Weight: 309.40200
  • Catalog: Research Areas Infection
  • Create Date: 2016-06-13 20:59:26
  • Modify Date: 2024-01-26 11:18:37
  • Atherosperminine(Atherospermine)is a nature occurring alkaloid, has antiplasmodial activities in vitro, with an IC50 of 5.80 μM. Atherosperminine is good reductants with the ability to chelate metals and presented pro-oxidant activity. Atherosperminine exerts a non-specific relaxant effect on the trachealis[1].

Name Atherosperminine
Synonyms 3,4-Dimethoxy-N,N-dimethyl-1-phenanthreneethanamine
[2-(3,4-dimethoxy-[1]phenanthryl)-ethyl]-dimethyl-amine
O-methylargentinine
[2-(3,4-Dimethoxy-[1]phenanthryl)-aethyl]-dimethyl-amin
1-[2-(N,N-dimethylaminoethyl)]-3,4-dimethoxyphenanthrene
phenanthrenes atherosperminine
atherospermine
N,N-Dimethyl-3,4-dimethoxyphenanthrene-1-ethanamine
Description Atherosperminine(Atherospermine)is a nature occurring alkaloid, has antiplasmodial activities in vitro, with an IC50 of 5.80 μM. Atherosperminine is good reductants with the ability to chelate metals and presented pro-oxidant activity. Atherosperminine exerts a non-specific relaxant effect on the trachealis[1].
Related Catalog
Target

IC50: 5.80 μM (P. falciparum, K1 strain)[1]

References

[1]. Ayu Afiqah Nasrullah, et al. Antiplasmodial Alkaloids from the Bark of Cryptocarya nigra (Lauraceae). Molecules. 2013 Jul; 18(7): 8009–8017.

[2]. C H Lin, et al. The relaxant actions on guinea-pig trachealis of atherosperminine isolated from Fissistigma. Eur J Pharmacol. 1993 Jun 11;237(1):109-16.

Density 1.109g/cm3
Boiling Point 466.1ºC at 760mmHg
Molecular Formula C20H23NO2
Molecular Weight 309.40200
Flash Point 161.5ºC
Exact Mass 309.17300
PSA 21.70000
LogP 4.11430
Storage condition 2-8℃
HS Code 2922199090
Precursor  4

DownStream  0

HS Code 2922199090
Summary 2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%