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491839-65-7

491839-65-7 structure
491839-65-7 structure
  • Name: FAK-IN-10
  • Chemical Name: WAY-320461
  • CAS Number: 491839-65-7
  • Molecular Formula: C15H10BrN3O2S
  • Molecular Weight: 376.2278
  • Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FAK
  • Create Date: 2023-01-21 17:28:45
  • Modify Date: 2024-09-13 15:44:33
  • FAK-IN-10 is an inhibitor of FAK with an IC50 of 76.3 μM. FAK-IN-10 exhibits antitumor activity against MCF-7 and A431 cell lines with IC50s of 4.23 and 0.78 μM,respectively[1].

Name WAY-320461
Synonyms Ethanone, 1-(4-bromophenyl)-2-[[5-(4-pyridinyl)-1,3,4-oxadiazol-2-yl]thio]-
Description FAK-IN-10 is an inhibitor of FAK with an IC50 of 76.3 μM. FAK-IN-10 exhibits antitumor activity against MCF-7 and A431 cell lines with IC50s of 4.23 and 0.78 μM,respectively[1].
Related Catalog
References

[1]. Zhang LR, et al. Synthesis, biological evaluation and molecular docking studies of novel 2-(1,3,4-oxadiazol-2-ylthio)-1-phenylethanone derivatives. Bioorg Med Chem. 2012 Jun 1;20(11):3615-21.  

Molecular Formula C15H10BrN3O2S
Molecular Weight 376.2278
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