688050-42-2

688050-42-2 structure

Name: BCR-ABL-IN-7
Chemical Name: WAY-328158
CAS Number: 688050-42-2
Molecular Formula: C₁₉H₁₆FN₃O₃S
Molecular Weight: 385.41
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK Bcr-Abl
Create Date: 2023-01-16 16:32:24
Modify Date: 2024-04-05 18:38:22
BCR-ABL-IN-7 (compound 4) is a WT and T315I mutant ABL kinases inhibitor. BCR-ABL-IN-7 effectively inhibits activities of WT and T315I mutant ABL kinases. BCR-ABL-IN-7 can be used for the research of chronic myeloid leukemia (CML) research[1].

Name	WAY-328158
Synonyms	3-Isoxazolecarboxamide, N-[3-(aminocarbonyl)-4,5,6,7-tetrahydrobenzo[b]thien-2-yl]-5-(4-fluorophenyl)-

Description	BCR-ABL-IN-7 (compound 4) is a WT and T315I mutant ABL kinases inhibitor. BCR-ABL-IN-7 effectively inhibits activities of WT and T315I mutant ABL kinases. BCR-ABL-IN-7 can be used for the research of chronic myeloid leukemia (CML) research[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Bcr-Abl
References	[1]. Cao R, et al. Discovery of 2-Acylaminothiophene-3-Carboxamides as Multitarget Inhibitors for BCR-ABL Kinase and Microtubules. J Chem Inf Model. 2015 Nov 23;55(11):2435-42.

Molecular Formula	C₁₉H₁₆FN₃O₃S
Molecular Weight	385.41