745033-86-7

745033-86-7 structure

Name: Antileishmanial agent-23
Chemical Name: WAY-624876
CAS Number: 745033-86-7
Molecular Formula: C₂₀H₁₇N₃O₄S₂
Molecular Weight: 427.50
Catalog: Research Areas Infection
Create Date: 2022-12-12 14:18:00
Modify Date: 2024-04-05 21:14:15
Antileishmanial agent-23 (compound G1/9) is a potent and selective trypanothione reductase (TR) inhibitor, with an IC50 of 2.24 ± 0.52 μM. Antileishmanial agent-23 inhibits the growth of Leishmania, Trypanosoma cruzi, and Trypanosoma brucei[1].

Name	WAY-624876
Synonyms	1,3,4-Oxadiazole, 2-(1,3-benzodioxol-5-yl)-5-[[[4,5-dihydro-2-(4-methoxyphenyl)-5-thiazolyl]methyl]thio]-

Description	Antileishmanial agent-23 (compound G1/9) is a potent and selective trypanothione reductase (TR) inhibitor, with an IC50 of 2.24 ± 0.52 μM. Antileishmanial agent-23 inhibits the growth of Leishmania, Trypanosoma cruzi, and Trypanosoma brucei[1].
Related Catalog	Research Areas >> Infection
References	[1]. Ilari A, et al. Toward a Drug Against All Kinetoplastids: From LeishBox to Specific and Potent Trypanothione Reductase Inhibitors. Mol Pharm. 2018 Aug 6;15(8):3069-3078.

Molecular Formula	C₂₀H₁₇N₃O₄S₂
Molecular Weight	427.50