58255-46-2
58255-46-2 structure
- Name: Dideoxy-amanitin
- Chemical Name: Dideoxy-amanitin
- CAS Number: 58255-46-2
- Molecular Formula: C39H54N10O12S
- Molecular Weight: 886.97
- Catalog: Signaling Pathways Antibody-drug Conjugate ADC Cytotoxin
- Create Date: 2023-02-05 13:33:40
- Modify Date: 2024-04-05 21:38:03
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Dideoxy-amanitin (compound 2), an α-Amanitin (HY-19610) derivative, is a potent and selective RNA polymerase II allosteric inhibitor with an IC50 value of 74.2 nM[1].
| Name | Dideoxy-amanitin |
|---|
| Description | Dideoxy-amanitin (compound 2), an α-Amanitin (HY-19610) derivative, is a potent and selective RNA polymerase II allosteric inhibitor with an IC50 value of 74.2 nM[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Dideoxy-amanitin (compound 2; 0.078-20 μM; 24 h) has cell cytotoxicity in CHO (Chinese hamster ovary) cells with an IC50 value of 0.3 μM[1]. Cell Viability Assay[1] Cell Line: CHO (Chinese hamster ovary) cells Concentration: 0.078-20 μM Incubation Time: 24 hours Result: Decreased cell proliferation in a dose-depengdent manner. |
| Molecular Formula | C39H54N10O12S |
|---|---|
| Molecular Weight | 886.97 |