2254483-95-7

2254483-95-7 structure
2254483-95-7 structure
  • Name: Malacidin A
  • Chemical Name: Malacidin A
  • CAS Number: 2254483-95-7
  • Molecular Formula: C56H88N12O20
  • Molecular Weight: 1249.37
  • Catalog: Signaling Pathways Anti-infection Bacterial
  • Create Date: 2022-11-27 11:41:50
  • Modify Date: 2025-08-27 17:38:27
  • Malacidin A is the calcium-dependent antibiotic (CDAs). Malacidin A is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria[1][2].

Name Malacidin A
Description Malacidin A is the calcium-dependent antibiotic (CDAs). Malacidin A is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria[1][2].
Related Catalog
In Vitro Malacidin A has antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) in a calcium-dependent manner[1]. Malacidin A (100-250 µg/mL) has broadly active against Gram-positive bacteria including multidrug-resistant pathogens and bacteria resistant to mechanistically diverse, clinically used antibiotics with MIC values of 0.1-2.0 µg/mL[1].
In Vivo Malacidin A (4 mg/kg; apply over the wound) has antibacterial activity and inhibits bacterial load in cutaneous wound infection mice[1]. Animal Model: Male Sprague Dawley rats (8 weeks old) with cutaneous wound infection model[1] Dosage: 4 mg/kg Administration: Apply over the wound Result: Had no observed bacterial burdens in the wounds.
Molecular Formula C56H88N12O20
Molecular Weight 1249.37
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