1527474-15-2
1527474-15-2 structure
- Name: PF-06455943
- Chemical Name: PF-06455943
- CAS Number: 1527474-15-2
- Molecular Formula: C17H14FN5O
- Molecular Weight: 323.32
- Catalog: Signaling Pathways Autophagy LRRK2
- Create Date: 2022-11-22 16:46:13
- Modify Date: 2025-08-22 12:23:27
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PF-06455943 is a leucine rich repeat kinase 2 (LRRK2) inhibitor with IC50 value of 3 nM. PF-06455943 also is a PET radioligand. PF-06455943 can be used for the research of ADME/neuro PK characterization and Parkinson disease (PD)[1][2].
| Name | PF-06455943 |
|---|
| Description | PF-06455943 is a leucine rich repeat kinase 2 (LRRK2) inhibitor with IC50 value of 3 nM. PF-06455943 also is a PET radioligand. PF-06455943 can be used for the research of ADME/neuro PK characterization and Parkinson disease (PD)[1][2]. |
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| Related Catalog | |
| In Vitro | PF-06455943 (Compound 22) has inhibition activity for LRRK2 with IC50 values of 3 nM (WT), 9 nM (G2019S) and 20 nM (cellular WCA), respectively[1]. |
| Molecular Formula | C17H14FN5O |
|---|---|
| Molecular Weight | 323.32 |