317328-17-9
317328-17-9 structure
- Name: ZINC00784494
- Chemical Name: ZINC00784494
- CAS Number: 317328-17-9
- Molecular Formula: C20H14N2O3S
- Molecular Weight: 362.40
- Catalog: Research Areas Cancer
- Create Date: 2022-12-18 20:21:03
- Modify Date: 2024-02-05 10:31:55
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ZINC00784494 is a specific Lipocalin-2 (LCN2) inhibitor. ZINC00784494 inhibits cell proliferation, cell viability and reduces AKT phosphorylation levels in SUM149 cells. ZINC00784494 has good potential for research in inflammatory breast cancer (IBC)[1].
| Name | ZINC00784494 |
|---|
| Description | ZINC00784494 is a specific Lipocalin-2 (LCN2) inhibitor. ZINC00784494 inhibits cell proliferation, cell viability and reduces AKT phosphorylation levels in SUM149 cells. ZINC00784494 has good potential for research in inflammatory breast cancer (IBC)[1]. |
|---|---|
| Related Catalog | |
| Target |
LCN2[1]. |
| In Vitro | ZINC00784494 (0.01-100 µM; 72 h) reduces cell proliferation and cell viability in SUM149 cells[1]. ZINC00784494 (1, 10 µM; 15 min, 1 h) reduces the p-Akt levels in SUM149 cells[1]. Cell Viability Assay[1] Cell Line: SUM149 cells Concentration: 0.01-100 µM Incubation Time: 72 h Result: Reduced cell viability at concentrations of 1 µM or lower. Western Blot Analysis[1] Cell Line: SUM149 cells Concentration: 1, 10 µM Incubation Time: 15 min, 1 h, 24 h Result: Reduced the p-Akt protein levels 15 min and 1 h and changes in the p-Akt protein levels were not observed at 24 h. |
| Molecular Formula | C20H14N2O3S |
|---|---|
| Molecular Weight | 362.40 |