945628-66-0

945628-66-0 structure

Name: 5'-ODMT cEt G Phosphoramidite (Amidite)
Chemical Name: 5'-ODMT cEt G Phosphoramidite (Amidite)
CAS Number: 945628-66-0
Molecular Formula: C₄₆H₅₆N₇O₉P
Molecular Weight: 881.95
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2023-01-14 07:33:19
Modify Date: 2024-07-21 19:37:54
5'-ODMT cEt G Phosphoramidite Amidite is a potent nucleic acid analog. 5'-ODMT cEt G Phosphoramidite Amidite shows excellent safety and antisense activity[1][2].

Name	5'-ODMT cEt G Phosphoramidite (Amidite)

Description	5'-ODMT cEt G Phosphoramidite Amidite is a potent nucleic acid analog. 5'-ODMT cEt G Phosphoramidite Amidite shows excellent safety and antisense activity[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Vasquez G, et al. Site-specific incorporation of 5'-methyl DNA enhances the therapeutic profile of gapmer ASOs. Nucleic Acids Res. 2021 Feb 26;49(4):1828-1839. [2]. Seth PP, et al. Synthesis and biophysical evaluation of 2',4'-constrained 2'O-methoxyethyl and 2',4'-constrained 2'O-ethyl nucleic acid analogues. J Org Chem. 2010 Mar 5;75(5):1569-81.

Molecular Formula	C₄₆H₅₆N₇O₉P
Molecular Weight	881.95