2254086-60-5

2254086-60-5 structure

Name: Tusamitamab ravtansine
Chemical Name: Tusamitamab ravtansine
CAS Number: 2254086-60-5
Molecular Formula:
Molecular Weight:
Catalog: Research Areas Cancer
Create Date: 2023-01-21 10:59:39
Modify Date: 2023-01-21 10:59:39
Tusamitamab ravtansine (SAR-408701) is a DM4 (HY-12454) anti-CEACAM5 antibody-drug conjugate (ADC). Tusamitamab ravtansine is composed of a humanized monoclonal antibody that binds carcinoembryonic antigen-related cell adhesion molecule-5 (CEACAM5) and a cytotoxic maytansinoid that selectively targets CEACAM5-expressing tumor cells[1].

Name	Tusamitamab ravtansine

Description	Tusamitamab ravtansine (SAR-408701) is a DM4 (HY-12454) anti-CEACAM5 antibody-drug conjugate (ADC). Tusamitamab ravtansine is composed of a humanized monoclonal antibody that binds carcinoembryonic antigen-related cell adhesion molecule-5 (CEACAM5) and a cytotoxic maytansinoid that selectively targets CEACAM5-expressing tumor cells[1].
Related Catalog	Research Areas >> Cancer
References	[1]. Gazzah A, et al. Safety, pharmacokinetics, and antitumor activity of the anti-CEACAM5-DM4 antibody-drug conjugate tusamitamab ravtansine (SAR408701) in patients with advanced solid tumors: first-in-human dose-escalation study. Ann Oncol. 2022 Apr;33(4):416-425.

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