470704-11-1

470704-11-1 structure
470704-11-1 structure
  • Name: 2F5 epitope
  • Chemical Name: 2F5 epitope
  • CAS Number: 470704-11-1
  • Molecular Formula: C76H113N17O22
  • Molecular Weight: 1616.81
  • Catalog: Signaling Pathways Anti-infection HIV
  • Create Date: 2023-03-07 00:22:25
  • Modify Date: 2024-04-07 20:55:07
  • 2F5 epitope, a peptide gp41 (659-671), comprises the entire epitope for one of the three known antibodies capable of neutralizing a broad spectrum of primary HIV-1 isolates and is the only such epitope that is sequential. 2F5 epitope is recognized by broadly neutralizing antibodies 2F5[1][2].

Name 2F5 epitope
Description 2F5 epitope, a peptide gp41 (659-671), comprises the entire epitope for one of the three known antibodies capable of neutralizing a broad spectrum of primary HIV-1 isolates and is the only such epitope that is sequential. 2F5 epitope is recognized by broadly neutralizing antibodies 2F5[1][2].
Related Catalog
References

[1]. Zohar Biron, et al. A monomeric 3(10)-helix is formed in water by a 13-residue peptide representing the neutralizing determinant of HIV-1 on gp41. Biochemistry. 2002 Oct 22;41(42):12687-96.  

[2]. Yougang Zhai, et al. Bovine papillomavirus-like particles presenting conserved epitopes from membrane-proximal external region of HIV-1 gp41 induced mucosal and systemic antibodies. Vaccine. 2013 Nov 4;31(46):5422-9.  

Molecular Formula C76H113N17O22
Molecular Weight 1616.81