94205-22-8
94205-22-8 structure
- Name: Anticancer agent 93
- Chemical Name: Anticancer agent 93
- CAS Number: 94205-22-8
- Molecular Formula: C16H10ClNO4
- Molecular Weight: 315.71
- Catalog: Research Areas Cancer
- Create Date: 2023-02-03 19:45:30
- Modify Date: 2024-01-16 09:42:14
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Anticancer agent 93 is a 4-Hydroxycoumarin derivative. Anticancer agent 93 can inhibit invasion and migration of lung cancer cells by modulating expression of epithelial-mesenchymal transition (EMT) effectors[1].
| Name | Anticancer agent 93 |
|---|
| Description | Anticancer agent 93 is a 4-Hydroxycoumarin derivative. Anticancer agent 93 can inhibit invasion and migration of lung cancer cells by modulating expression of epithelial-mesenchymal transition (EMT) effectors[1]. |
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| Related Catalog | |
| In Vitro | Anticancer agent 93 (compound 4h) (5-15 μM; 24 h) significantly inhibits A549 cell invasion by ~ 50%[1]. Anticancer agent 93 (15 μM; 24-72 h) significantly inhibits A549 cell migration[1]. Anticancer agent 93 (5-15 μM; 4 h) inhibits lung cancer cell motility by downregulating EMT markers[1]. Western Blot Analysis[1] Cell Line: A549 cells Concentration: 5, 10, 15 μM Incubation Time: 24 hours Result: Decreased expression of N-cadherin and E-cadherin. |
| References |
| Molecular Formula | C16H10ClNO4 |
|---|---|
| Molecular Weight | 315.71 |